Forschungsbericht - Detailinformation zum Projekt

project title

Immunopharmacology

abstract

We are interested in the role of apoptosis and autophagy in inflammatory diseases and cancer. Several diseases serve as models to study such processes. In particular, we investigate pathogenic mechanisms of the following diseases: Atopic dermatitis, hypereosinophilic syndromes, eosinophilic esophagitis, cystic fibrosis, sepsis, and malignant melanoma. Our research goal is the identification of new drug targets for future therapeutic approaches in these diseases. Besides the pathogenic aspects of our research, we have developed several in vitro and in vivo test systems to determine potential effects of a given drug on the immune system. Moreover, we are involved in several clinical drug studies. Our research requires a network of physician-scientists from many different clinics. Most of the participating groups are located at the Medical Faculty of the University of Bern. Results of these collaborative interactions are seen in the abstracts of our group website, which briefly describe our research activities in 2009.

project team

Prof. Dr. Dr. med. Hans-Uwe Simon (PL), Dr. Sébastien Conus, Dr. Barbara Geering, Dr. Christina Stöckle, Technician Inès Schmid, Technician Evelyne Kozlowski, PhD student Cristina Mihalache, PhD student Elena Federzoni, PhD student Dipak Maskey, PhD student He Liu, PhD student Zhaoyue He

project duration

01.2000 - 12.2015
state:ongoing

university unit

Institut für Pharmakologie

research area

Medicine, Pharmacology and Pharmacy 

index terms

Allergy, Apoptosis, Autophagy, Immunopharmacology, Inflammation, Signalling.

last update: 22.01.2010

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