Forschungsbericht - Detailinformation zum Projekt

project title

Regulation of the IP3 receptor isoforms

abstract

Hormones and growth factors trigger the production of inositol 1,4,5-triphosphate (IP3). IP3 binds to its receptor, a calcium channel, to release calcium from internal stores. These calcium signals participate in many important aspects of cellular physiology such as metabolism regulation, secretion, genes transcription, cell proliferation and transformation. Our group investigates how the IP3 receptor functions and communicates with other proteins within the cell.

project team

Prof. Jean-François Dufour (PL)

project duration

11.2005 - 11.2008
state:ongoing

university unit

Institut für Klinische Pharmakologie

research area

Natural Sciences, Biology 

index terms

calcium, channel, signal

last update: 14.12.2005

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