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Prof. Dr. Lars French

Fakultäten » Medizinische Fakultät » Dermatologische Klinik » Prof. Dr. Lars French

Current research projects

Project leader Project title
Contassot Study of the role of the inflammasome in the pathogenesis of acute graft versus host disease
Study of the role of the NLRP3 inflammasome in the pathogenesis of acne vulgaris
Mechanisms involved in keratinocyte apoptosis in patients suffering from toxic epidermal necrolysis
Role of innate immunity in the physiopathology of severe averse reactions to drugs
Development and molecular and immunological characterization of an autochtonous mouse melanoma model
Study of the role of IL1 in the pathogenesis of acneiform eruptions in cancer patients treated with EGFR inhibitors
Role of innate immunity receptors in immune responses to fungi in the skin
Study of the role of the inflammasome and IL1 in the pathogenesis of cutaneous melanoma
Contassot Gehrke Characterization of the molecular pathways linking mitochondrial damages and inflammatory responses

Completed research projects

Project leader Project title
Akdis (Akdis CA.) Investigation of cellular and molecular effector mechanisms in chronic sinusitis
Ballmer-Weber (Ballmer-Weber B.) Molecular analysis of IgE antibodies in pollen related food allergies in Europe
(Ballmer-Weber B.) International Collaborative Soybean Allergenicity Study
(Ballmer-Weber B.) REDALL: Reduced allergenicity of processed foos containing animal allergens
(Ballmer-Weber B.) Europrevall (The Prevalence, Cost and Basis of Food Allergy Across Europe)
(Ballmer-Weber B.) Exemption from allergen labelling for natural mixed tocopherol (E 306), phytosterols and phytosterol esters for a range of food applications.
(Ballmer-Weber B.) Development of specific immunotherapy in pollen related food allergy: low IgE binding carrot allergens as potential vaccines
(Ballmer-Weber B.) Pen a 1: Development of specific immunotherapy in severe food allergy taking shrimp as a model food and determination of threshold dose in shrimp allergy
(Ballmer-Weber B.) FAREDAT: Food allergy risk evaluation based on improved diagnosis, allergens and test methods
Dummer (Dummer R.) Imiquimod in skin cancers
(Dummer R.) Human melanoma - from transcriptome to tumor biology
(Dummer R.) Photochemoprevention of cutaneous UVB damage with topically applied green tea polyphenols
(Dummer R.) Replicating viruses in cutaneous neoplasms
(Dummer R.) Longitudinal analysis of immune escape and gene expression profiles in human melanoma
(Dummer R.) Interferon signaling in lymphoma, molecular analysis and evaluation of viral oncolysis as treatment approach
(Dummer R.) Interferon Signalling bei kutanen T-Zell-Lymphomen
(Dummer R.) Antigen-Präsentation beim Melanom
Kempf (Kempf W.) Gene profiling in epithelial skin neoplasms of transplant recipients
(Kempf W.) Diagnostic and prognostic significance of genomic alterations cutaneous T-cell lymphomas
(Kempf W.) Identification of infectious agents as causative factors in cutaneous B-cell lymphomas
(Kempf W.) Identification of tumor regression mediating genes in CD30 positive cutaneous T-cell lymphomas
Kündig (Kündig Th.) Allergen specific immunotherapy by intralymphatic administration
(Kündig Th.) Allergen specific immunotherapy using Virus Like Particles (VLP) and ISS (QbG10)
(Kündig Th.) Allergen specific immunotherapy using allergen fusion proteins
(Kündig Th.) Immunotherapy of chronic Hepatitis B
(Kündig Th.) Influencing the immune response by antigen kinetics
(Kündig Th.) Attempting antigen specific tolerance induction in Type IV allergy to nickel
(Kündig Th.) Treatment of atopic dermatitis by antimicrobial fabrics
(Kündig Th.) Novel applications for anti-histamines
(Kündig Th.) Treatment of inflammatory skin disease by NF-kappaB decoys
Nestle (Nestle F.) "Role of IL-15 and IL-2 in psoriasis and other immune diseases"
Schmid (Schmid P.) Fungal allergy in atopic dermatitis
(Schmid P.) SAPALDIA II Cohort Study; Impact of environmental and personal risk factors on the occurence, course, remission and progression of respiratory diseases in the Swiss population.
(Schmid P.) SCARPOL II; Swiss Surveillance Program of Childhood Allergy and Respiratory Symptoms with respect to airpollution and climate.