Prof. Dr. Reinhard Seger

Current Research Projects

Project Leader	Project Title
Reichenbach	Role of Neutrophil Extracellular Traps (NETs) in Aspergillus infection and granulomatous inflammation in CGD
Siler	Development of a gammaretroviral vector for gene replacement therapy of the p47phox-deficient form of Chronic Granulomatous Disease (CGD)

Completed Research Projects

Project Leader	Project Title
Berger	Latent Epstein-Barr virus infection: Can cognate antigen trigger productive EBV infection and cause growth transformation of responding B lymphocytes?
Berger Nadal Berli	Significance of the 30 base pair dletion variants of the Epstein-Barr virus (EBV) encoded latent membrans protein 1 in EBV-mediated oncogenesis
Hossle	Natural tissue-specific gene regulation after therapeutic gene transfer in chronic granulomatous disease (CGD)
	Oligonucleotide-mediated targeted gene repair of X-linked chronic granulomatous disease
	Gene therapy in children with X-linked chronic granulomatous disease (CGD)
	Gene therapy in children with X-linked chronic granulomatous disease (CGD): GMP
	Development of clinically applicable protocols for transitory and permanent somatic gene therapy in chronic granulomatous disease
Nadal Berger Zingg Berli	Quantifizierung von Epstein-Barr-Virus (EBV) bei Immundefizienten und Patienten mit EBV-assoziierten Tumoren
Nadal Zingg Berli	Rolle von Zyto- und Chemokinen bei der Entstehung des Kaposi-Sarkoms und als Angriffspunkte für dessen Therapie
Reichenbach	Gene therapy for chronic granulomatous disease: Optimization of retroviral gene expression in myeloid progenitors
Siler	Monitoring of pediatric CGD gene therapy patients
	Retroviral delivery of episomal vectors to hematopoietic stem cells; a feasibility study