Prof. Dr. Reinhard Seger

Fakultäten » Medizinische Fakultät » Kinderspital Zürich: Medizinische Klinik » Immunologie, Abteilung » Prof. Dr. Reinhard Seger

Current research projects

Project leader	Project title
Pachlopnik Schmid	Treating hemophagocytic lymphohistiocytosis (HLH) by blocking interferon gamma
Reichenbach	Role of macroautophagy in chronic granulomatous disease (CGD) and correction of the defect
Seger Reichenbach	Using iPSC technology to model human CGD disease: A feasibility study
Siler	Development of a gammaretroviral vector for gene replacement therapy of the p47phox-deficient form of Chronic Granulomatous Disease (CGD)

Completed research projects

Project leader	Project title
Berger	Latent Epstein-Barr virus infection: Can cognate antigen trigger productive EBV infection and cause growth transformation of responding B lymphocytes?
Berger Nadal Berli	Significance of the 30 base pair dletion variants of the Epstein-Barr virus (EBV) encoded latent membrans protein 1 in EBV-mediated oncogenesis
Hossle	Natural tissue-specific gene regulation after therapeutic gene transfer in chronic granulomatous disease (CGD)
	Oligonucleotide-mediated targeted gene repair of X-linked chronic granulomatous disease
	Gene therapy in children with X-linked chronic granulomatous disease (CGD)
	Gene therapy in children with X-linked chronic granulomatous disease (CGD): GMP
	Development of clinically applicable protocols for transitory and permanent somatic gene therapy in chronic granulomatous disease
Nadal Berger Zingg Berli	Quantifizierung von Epstein-Barr-Virus (EBV) bei Immundefizienten und Patienten mit EBV-assoziierten Tumoren
Nadal Zingg Berli	Rolle von Zyto- und Chemokinen bei der Entstehung des Kaposi-Sarkoms und als Angriffspunkte für dessen Therapie
Reichenbach	Gene therapy for chronic granulomatous disease: Optimization of retroviral gene expression in myeloid progenitors
	Role of Neutrophil Extracellular Traps (NETs) in Aspergillus infection and granulomatous inflammation in CGD
Siler	Development of a gammaretroviral vector for gene replacement therapy of the p47phox-deficient form of Chronic Granulomatous Disease (CGD)
	Monitoring of pediatric CGD gene therapy patients
	Retroviral delivery of episomal vectors to hematopoietic stem cells; a feasibility study
	Monitoring of pediatric CGD gene therapy patients