Current Research Projects

Project Leader Project Title
Reichenbach Role of Neutrophil Extracellular Traps (NETs) in Aspergillus infection and granulomatous inflammation in CGD
Siler Development of a gammaretroviral vector for gene replacement therapy of the p47phox-deficient form of Chronic Granulomatous Disease (CGD)

Completed Research Projects

Project Leader Project Title
Berger Latent Epstein-Barr virus infection: Can cognate antigen trigger productive EBV infection and cause growth transformation of responding B lymphocytes?
Berger Nadal Berli Significance of the 30 base pair dletion variants of the Epstein-Barr virus (EBV) encoded latent membrans protein 1 in EBV-mediated oncogenesis
Hossle Natural tissue-specific gene regulation after therapeutic gene transfer in chronic granulomatous disease (CGD)
Oligonucleotide-mediated targeted gene repair of X-linked chronic granulomatous disease
Gene therapy in children with X-linked chronic granulomatous disease (CGD)
Gene therapy in children with X-linked chronic granulomatous disease (CGD): GMP
Development of clinically applicable protocols for transitory and permanent somatic gene therapy in chronic granulomatous disease
Nadal Berger Zingg Berli Quantifizierung von Epstein-Barr-Virus (EBV) bei Immundefizienten und Patienten mit EBV-assoziierten Tumoren
Nadal Zingg Berli Rolle von Zyto- und Chemokinen bei der Entstehung des Kaposi-Sarkoms und als Angriffspunkte für dessen Therapie
Reichenbach Gene therapy for chronic granulomatous disease: Optimization of retroviral gene expression in myeloid progenitors
Siler Monitoring of pediatric CGD gene therapy patients
Retroviral delivery of episomal vectors to hematopoietic stem cells; a feasibility study