Prof. Dr. Felix Niggli

Current Research Projects

Project Leader	Project Title
Bernasconi	A Molecular ZIP Code for Vascular Targeting of Pediatric Embryonal Tumors
Niggli	Innovative treatment approaches for Ewing's sarcoma
Schäfer	Molecular basis of sarcoma tumor development
	Oncogenic fusion proteins as therapeutic targets in pediatric sarcomas

Completed Research Projects

Project Leader	Project Title
Arcaro	Cancer and Cell Biology
	Identification of new molecular targets for human medulloblastoma using RNA interference screening
	Signalling by class II phosphoinositide 3-kinases downstream of receptor tyrosine kinases
Betts	Investigation of the relationship between genetic events in childhood embryonal tumours
Grotzer	Inhibition of Insulin-like Growth Factor I Receptor Signaling in Pediatric Teratoid/Rhabdoid CNS Tumors
	Novel Therapeutic Approaches for Central Nervous System Primitive Neuroectodermal Tumors of Childhood
	Neurotrophin-Receptors and Oncogene MYC in Central Nervous System Primitive Neuroectodermal Tumors of Childhood
	Central Tumor Bank für Children’s Malignant Tumors of the Swiss Pediatric Oncology Group (SPOG)
Nadal Niggli	Investigation of lymphomagenesis associated to Epstein-Barr virus infection using DNA microchip technology
Niggli	Establishing of minimal residual disease techniques in childhood acute lymphoblastic leukemia and their application in an international clinical treatment trial
	Generation of a Wilms tumor mouse model: role of wnt signaling
Niggli Nadal	Epstein-Barr Virus (EBV) Whole Genome Expression profiling in EBV-associated Lymphomas: Development of an Oligonucleotide Microarray and Applications.
Schäfer	Subclass prediction in paediatric acute lymphoblastic leukaemia using gene expression profiling