Albisetti
Fakultäten » Medizinische Fakultät » Kinderspital Zürich: Medizinische Klinik » Hämatologie, Abteilung » PD Dr. Markus Schmugge Liner » Albisetti
Completed research project
| Title / Titel | Vascular complications of Port-à-Cath devices in paediatric oncology patients | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Abstract (PDF, 14 KB) | |||||||||
| Summary / Zusammenfassung | Port-à-Cath (PAC) devices are essential components of modern management in paediatric oncology. However, a PAC is possibly associated with an increased risk of thrombosis, likely causing long-term morbidity. The incidence, predictors and outcome of PAC-related thrombosis are not well defined. PAC-related thrombosis and postthrombotic syndrome (PTS) are investigated in a large paediatric oncology population. The study population is a consecutive cohort of children diagnosed with cancer, and with a PAC implanted at diagnosis or shortly after. Included children are evaluated for the presence of PAC-related thrombosis by magnetic resonance (MR) venography of the upper deep venous system, congenital prothrombotic risk factors, and PTS using a published paediatric score (Kuhle et al 2003). Preliminary results show that PAC-related thrombosis occurs in one third of paediatric oncology patients. Thrombotic complications persist over time following PAC removal and predispose some of these children to the development of PTS. The continuation of this study will define the long term morbidity of PAC-related thrombosis in paediatric oncology. Weitere Informationen |
||||||||
| Project leadership and contacts / Projektleitung und Kontakte |
|
||||||||
| Funding source(s) / Unterstützt durch |
Foundation |
||||||||
| Duration of Project / Projektdauer | Jan 2005 to Dec 2010 |