Jäncke
Fakultäten » Philosophische Fakultät » Psychologisches Institut » Neuropsychologie » Prof. Dr. Lutz Jäncke » Jäncke
Completed research project
| Title / Titel | Short-term and long-term plasticity in the auditory system | ||
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| Abstract (PDF, 14 KB) | |||
| Summary / Zusammenfassung | The tremendous pace in neuroscience has born several new research areas. One of these new fields involves the analysis of relationships between brain structure and function in humans, a research field which has been entitled as “Cognitive Neuroanatomy” by Sandra Witelson (1992). The second new research field is the analysis of the functional plasticity of the human nervous system both due to external stimulation and to developmental influences. While in the beginning, researchers looked for structure-function relationships by analysing various parts of post mortem brains (classical morphometry), the tremendous pace of development in brain imaging technologies has revolutionised our ability to investigate brain structure and function. Techniques are now available to capture features of the anatomy and function of whole brain scales, mapping neuronal dynamics and gene expression as well as growth and degeneration processes that span multi-layer time scales both for post mortem and in vivo cases. The number of brain imaging investigations is also increasing exponentially. A major goal of these new studies is to analyse how the whole brain or parts of it varies across age, gender, disease, in large human populations, due to external stimulation, or whether there are between-hemisphere differences. To tackle these questions, many laboratories are using sophisticated methods for brain image analysis. While in former times neuroanatomy was an exclusive domain for neuroanatomists, meanwhile engineering approaches drawn from computer vision, image analysis, computer graphics, and artificial intelligence research fields are required to analyse and visualise anatomical brain data. Novel methods are continuously developed to uncover new patterns of altered brain structures and functions in various populations. Basically, there are two main branches of in vivo anatomical analysis which are currently followed: 1. The classical in vivo morphometry and 2. various variants of voxel-based morphometry techniques. However, although these approaches are currently succesfully used in several laboratories there is an apparant lack of research which apply these new techniques in the context of brain development during early and late childhood. This is exactly the focus of our research project. But before we will describe our own research proposal we will shortly describe the current status of “cognitive neuroanatomy” with special emphasis on developmental aspects. | ||
| Publications / Publikationen | Baumann, S., Meyer, M., & Jancke, L. (2008). Enhancement of auditory-evoked potentials in musicians reflects an influence of expertise but not selective attention. J Cogn Neurosci, 20(12), 2238-2249.Schmidt, C. F., Zaehle, T., Meyer, M., Geiser, E., Boesiger, P., & Jancke, L. (2008). Silent and continuous fMRI scanning differentially modulate activation in an auditory language comprehension task. Hum Brain Mapp, 29(1), 46-56.Zaehle, T., Geiser, E., Alter, K., Jancke, L., & Meyer, M. (2008). Segmental processing in the human auditory dorsal stream. Brain Res, 1220, 179-190.Beeli, G., Esslen, M., & Jancke, L. (2008). Time course of neural activity correlated with colored-hearing synesthesia. Cereb Cortex, 18(2), 379-385.Geiser, E., Zaehle, T., Jancke, L., & Meyer, M. (2008). The neural correlate of speech rhythm as evidenced by metrical speech processing. J Cogn Neurosci, 20(3), 541-552.Hanggi, J., Beeli, G., Oechslin, M. S., & Jancke, L. (2008). The multiple synaesthete E.S.: neuroanatomical basis of interval-taste and tone-colour synaesthesia. Neuroimage, 43(2), 192-203.Jancke, L. (2008). Music, memory and emotion. J Biol, 7(6), 21.Meyer, M., Baumann, S., Marchina, S., & Jancke, L. (2007). Hemodynamic responses in human multisensory and auditory association cortex to purely visual stimulation. BMC Neurosci, 8, 14.Kast, M., Meyer, M., Vogeli, C., Gross, M., & Jancke, L. (2007). Computer-based multisensory learning in children with developmental dyslexia. Restor Neurol Neurosci, 25(3-4), 355-369.Meyer, M., Elmer, S., Baumann, S., & Jancke, L. (2007). Short-term plasticity in the auditory system: differential neural responses to perception and imagery of speech and music. Restor Neurol Neurosci, 25(3-4), 411-431.Zaehle, T., Jancke, L., & Meyer, M. (2007). Electrical brain imaging evidences left auditory cortex involvement in speech and non-speech discrimination based on temporal features. Behav Brain Funct, 3, 63.Zaehle, T., Schmidt, C. F., Meyer, M., Baumann, S., Baltes, C., Boesiger, P. et al. (2007). Comparison of "silent" clustered and sparse temporal fMRI acquisitions in tonal and speech perception tasks. Neuroimage, 37(4), 1195-1204.Baumann, S., Koeneke, S., Schmidt, C. F., Meyer, M., Lutz, K., & Jancke, L. (2007). A network for audio-motor coordination in skilled pianists and non-musicians. Brain Res, 1161, 65-78.Beeli, G., Esslen, M., & Jancke, L. (2007). Frequency correlates in grapheme-color synaesthesia. Psychol Sci, 18(9), 788-792.Baumgartner, T., Lutz, K., Schmidt, C. F., & Jancke, L. (2006). The emotional power of music: how music enhances the feeling of affective pictures. Brain Res, 1075(1), 151-164.Baumgartner, T., Esslen, M., & Jancke, L. (2006). From emotion perception to emotion experience: emotions evoked by pictures and classical music. Int J Psychophysiol, 60(1), 34-43.Jancke, L., Baumann, S., Koeneke, S., Meyer, M., Laeng, B., Peters, M. et al. (2006). Neural control of playing a reversed piano: empirical evidence for an unusual cortical organization of musical functions. Neuroreport, 17(4), 447-451.Jancke, L., Lutz, K., & Koeneke, S. (2006). Converging evidence of ERD/ERS and BOLD responses in motor control research. Prog Brain Res, 159, 261-271.Beeli, G., Esslen, M., & Jancke, L. (2005). Synaesthesia: when coloured sounds taste sweet. Nature, 434(7029), 38.Bunzeck, N., Wuestenberg, T., Lutz, K., Heinze, H. J., & Jancke, L. (2005). Scanning silence: mental imagery of complex sounds. Neuroimage, 26(4), 1119-1127.Zaehle, T., Wustenberg, T., Meyer, M., & Jancke, L. (2004). Evidence for rapid auditory perception as the foundation of speech processing: a sparse temporal sampling fMRI study. Eur J Neurosci, 20(9), 2447-2456. | ||
| Project leadership and contacts / Projektleitung und Kontakte |
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| Funding source(s) / Unterstützt durch |
SNF (Personen- und Projektförderung) This project has been extended by the SNF due the rated excellence of the scientific work. |
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| Duration of Project / Projektdauer | Sep 2003 to Jan 2009 |