Hegemann
Fakultäten » Medizinische Fakultät » Ohren-, Nasen-, Hals- und Gesichtschirurgie, Klinik für » Prof. Dr. Norbert Dillier » Hegemann
Completed research project
| Title / Titel | Ocular motor plasticy following vestibular tone asymmetry in humans | ||
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| Abstract (PDF, 14 KB) | |||
| Summary / Zusammenfassung | The overall goal of this project is to better understand the role of the oculomotor neural integrator in processing vestibular information driving the vestibuloocular reflex. Alexander’s law represents a modification of those NIs that can be observed during spontaneous nystagmus due to UVD or vestibular stimulation/inhibition. In case of peripheral vestibular nystagmus it has only been investigated for the horizontal nystagmus components. It is unclear whether the vertical and torsional components of nystagmus also exhibit AL, to what extend they are affected and whether these components are coordinated to optimally serve the needs of the visual system. It is still a matter of debate whether AL is an adaptive process to overcome visual disturbances due to vestibular nystagmus or an intrinsic property of the oculomotor control system. Since AL is due to changes in NI function it gives us the unique opportunity to assess neural processing of vestibular signals by the NI. We aim to give the first complete three-dimensional description of AL and to derive a cybernetic model of the 3-D neural integrator network. | ||
| Publications / Publikationen | Hegemann, S., Retinal image stabilization during caloric nystagmus reduces vertigo. Barany Society XXIII international congress, Paris, France, 2004. Hegemann, S., Shelhamer, M., Kramer, P.D. and Zee, D.S., Adaptation of the phase of the human linear vestibulo-ocular reflex (LVOR) and effects on the oculomotor neural integrator, Journal of Vestibular Research, 10 (2000) 239-47. Hegemann, S., Shelhamer, M.J. and Zee, D.S., Phase adaptation of the linear vestibulo-ocular reflex, Ann N Y Acad Sci, 871 (1999) 414-6. Lamprecht, J. and Hegemann, S., Ein neuartiges Verfahren zur Beseitigung des Drehschwindels während des Nystagmus., Otorhinolaryngol Nova, 3 (1993) 280. Hegemann S, Straumann D, Bockisch C, JARO (2007)Weitere Informationen |
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| Keywords / Suchbegriffe | Alexander’s law, nystagmus, vestibulo-ocular reflex | ||
| Project leadership and contacts / Projektleitung und Kontakte |
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| Other links to external web pages | http://www.orl.unispital.ch | ||
| Funding source(s) / Unterstützt durch |
SNF (Personen- und Projektförderung) 320000_122535/1 |
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| Duration of Project / Projektdauer | Oct 2008 to Sep 2011 |