Fakultäten » Medizinische Fakultät » Dermatologische Klinik » Prof. Dr. Barbara Ballmer-Weber » Ballmer-Weber
| Title / Titel | Relevance of Lipid Transfer Protein sensitisation in celeriac and mugwort pollen allergy | ||||||
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| Abstract (PDF, 14 KB) | |||||||
| Original title / Originaltitel | Relevanz des Lipid Transfer Proteins (LTP) bei der Sellerie- und Beifussallergie. | ||||||
| Summary / Zusammenfassung | Lipid transfer proteins (LTP) are panallergens in plant foods. Sensitisation to LTP is particularly frequent in Mediterranean countries and associated with an increased risk for severe systemic allergic reactions. Patients with mugwort pollen related celeriac allergy often suffer from systemic allergic reactions up to anaphylaxis upon celeriac ingestion. The cross-reacting allergen between mugwort pollen and celeriac, however, has not yet been identified. LTP is a possible candidate. The current project investigates cross-reacting allergens including LTP in mugwort pollen and celeriac allergic patients. | ||||||
| Publications / Publikationen | Ballmer-Weber BK, Vieths S, Lüttkopf D, Heuschmann P, Wüthrich B: Celery allergy confirmed by DPBCFC. A clinical study in 32 subjects with a history of adverse reactions toBallmer-Weber BK, Hoffmann A, Wüthrich B, Lüttkopf D, Pompei C, Wangorsch A, Kästern M, Vieths S. Influence of food processing on the allergenicity of celery: DBPCFC with celery spice and cooked celery in patients with celery allergy. Allergy 2002; 57:228-235.Lüttkopf D, Ballmer-Weber BK, Wüthrich B, Vieths S. Celery Allergens in Patients with Positive Double-Blind Placebo-Controlled Food Challenge. J Allergy Clin Immun 2000; 106: 390-399.Bauermeister K, Ballmer-Weber BK, Bublin M, Fritsche P, Hanschmann KMO, Hoffmann-Sommergruber K, Lidholm J, Oberhuber C, Randow S, Holzhauser T, Vieths S. Assessment of component resolved in vitro diagnosis of celeriac allergy, J Allergy Clin Immunology 2009; 124: 1273-1281, | ||||||
| Keywords / Suchbegriffe | celeriac allergy, mugwort pollen, LTP | ||||||
| Project leadership and contacts / Projektleitung und Kontakte |
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| Funding source(s) / Unterstützt durch |
Foundation |
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| In collaboration with / In Zusammenarbeit mit |
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| Duration of Project / Projektdauer | Apr 2009 to Mar 2012 |