Dillier Lai
Fakultäten » Medizinische Fakultät » Ohren-, Nasen-, Hals- und Gesichtschirurgie, Klinik für » Prof. Dr. Norbert Dillier » Dillier Lai
Completed research project
| Title / Titel | Functional Characterization of Neural Activity Patterns in Patients with Cochlear Implants and Auditory Brainstem Implants | ||||||
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| Abstract (PDF, 14 KB) | |||||||
| Summary / Zusammenfassung | Cochlear implant systems are successful examples of biomedical engineering technology. However, the challenges to design and apply implantable auditory prostheses which generate spatiotemporal patterns of electrically stimulated neural elements within the human cochlea or the auditory brainstem are still manifold and have only partly been solved. The propagation of the neural excitation through the ascending auditory pathway and its representation and perception by the cortical central processing system is still not fully understood. While the technical progress and the accumulated experience nowadays allow more complex and sophisticated devices to be manufactured than was conceivable in the early years of cochlear implant research, there still exist a number of key problems which have to be solved in order to provide the average users of these systems with improved benefit for speech communication and overall life quality improvement. The quality of the perceived sounds and thus the amount of speech recognition ability of an implanted patient depends on technological, physiological, surgical, etiological and other factors which very often are unknown. One of the goals of this research project is to investigate some of these unknown factors and to develop a more complete understanding of the mechanisms underlying neural excitation with implanted electrode arrays, to relate those mechanisms to psychoacoustic correlates of electrical stimulation and to derive improved strategies of speech coding and device fitting procedures for these devices. In addition to earlier work which was limited to patients with cochlear implants (CI) this project also includes studies with auditory brainstem implants (ABI) where the problem of finding an optimal stimulus configuration and speech processing strategy is even more difficult to solve than for cochlear implants. Weitere Informationen |
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| Publications / Publikationen | Dillier N, Lai WK, Almqvist B, Frohne C, Müller-Deile J, Stecker M, und von Wallenberg EL (2002) Measurement of the Electrically Evoked Compound Action Potential via a Neural Response Telemetry System. Ann Otol Rhinol Laryngol 111: 407-414.Lai WK, und Dillier N (2000) A Simple Two-Component Model of the Electrically Evoked Compound Action Potential in the Human Cochlea. Audiol Neurootol 6: 333-345Lai, W.K. (1999), An NRT Cookbook. Guidelines for making NRT measurements, Version 2.04 (Copyright: Cochlear AG, Basel).Weitere Informationen | ||||||
| Keywords / Suchbegriffe | Neurosciences, neurostimulator, auditory prostheses, cochlear implant, auditory brainstem implant, NRT, speech coding | ||||||
| Project leadership and contacts / Projektleitung und Kontakte |
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| Funding source(s) / Unterstützt durch |
SNF (Personen- und Projektförderung) |
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| In collaboration with / In Zusammenarbeit mit |
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| Duration of Project / Projektdauer | Oct 1996 to Sep 2004 |