Wüthrich Ballmer-Weber
Fakultäten » Medizinische Fakultät » Dermatologische Klinik » Prof. Dr. Brunello Wüthrich (emeritiert) » Wüthrich Ballmer-Weber
Completed research project
| Title / Titel | Adverse Reactions to Food | ||||
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| Abstract (PDF, 14 KB) | |||||
| Summary / Zusammenfassung | The general objectives of the research project are 1)to identify and characterize in hazelnut, celery and prunoideae fruits the major allergens that give rise to symptoms in the clinic, 2) to prepare diagnostic extracts with higher sensitivity and specificity, which will allow new improved diagnostic methods and 3) to improve the ability of the food industry to develop products of reduced allergenic potential. The task of the Allergy Unit of Zürich is to select patients with real allergic reactions to hazelnut and celery by a sequence determination starting with patient's history, skin tests and double-blind placebo-controlled food challenge (DBPCFC). Furthermore, these patients are tested with new extracts to determine if the new extracts do have a better sensitivity and specificity. Finally the selected patients are retested by DBPCFC with industrially processed food (i.e. celery spice or roasted hazelnuts) in order to define the allergenicity of the processed food. |
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| Publications / Publikationen | Ballmer-Weber BK, Vieths S., Wüthrich B: Sellerieallergie: Bestätigung der klinisch relevanten Sensibilisierung mittels DBPCFC. Mainzer Allergie-Workshop. 12.-13.3.1999.Ballmer-Weber BK, Vieths S., Lüttkopf D, Wüthrich B: Confirmation of the clinical relevant sensitisation to celery by double-blind placebo-controlled food challenge (DBPCFC). . EAACI, Brussels, 3.-7.7.1999.Ispano M, Wüthrich B, Ansaloni R, Vannucci L, Ballmer-Weber BK, Farioli L, Scibilia J, Ortolani C, Pastorello EA: Hazelnut allergy: double-blind placebo-controlled food challenge study and allergen characterisation. EAACI, Brussels, 3.-7.7.1999.Ballmer-Weber BK, Vieths S, Lüttkopf D, Bucher C, Wüthrich B: Haselnussallergie: Validierung der diagnostischen Verfahren anhand er doppelblinden plazebokontrollierten Nahrungsmittelprovokation. Allergologie. In press.Ortolani C, Ballmer-Weber BK, Skamstrup Hansen K, Ispano M, Wüthrich B, Bindslev-Jensen C, Ansaloni R, Vannuci L, Pravettoni V, Scibilia J, Poulsen LK, Pastorello E: Hazelnut Allergy: A double-blind placebo-controlled food challenge multicenter study. J Allergy Clin Immun. In press. | ||||
| Keywords / Suchbegriffe | Transplantation Medicine, Immunology | ||||
| Project leadership and contacts / Projektleitung und Kontakte |
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| Funding source(s) / Unterstützt durch |
EU, Others |
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| Duration of Project / Projektdauer | Sep 1997 to Sep 2000 |