Niggli Nadal

Fakultäten » Medizinische Fakultät » Kinderspital Zürich: Medizinische Klinik » Infektiologie, Abteilung » Prof. Dr. David Nadal » Niggli Nadal

Completed research project

Title / Titel	Epstein-Barr virus (EBV) whole genome expression profiling in EBV-associated tumor formation
PDF	Abstract (PDF, 14 KB)
Original title / Originaltitel	EBV whole genome expression profiling in EBV-associated tumor formation
Summary / Zusammenfassung	Epstein-Barr virus (EBV) is associated to a variety of tumours. The formation of EBV-associated tumors is significantly driven by the interplay of so far incompletely identified viral and human factors and that the essential EBV factors are determined by viral gene expression profiles exhibited during specific as yet not fully characterized circumstances. The goal ist to establish a so far commercially not available tool, i.e. a DNA microarray chip featuring the complete set of genes of the EBV in order to allow for comprehensive identification of viral gene expression profiles essential for the formation of EBV associated lymphomas.
Project leadership and contacts / Projektleitung und Kontakte	PD Dr. F. Niggli (Project Leader) felix.niggli@kispi.uzh.ch Prof. Dr. D. Nadal (Project Leader) david.nadal@kispi.uzh.ch
Funding source(s) / Unterstützt durch	Foundation Cancer League Kanton of Zurich
Duration of Project / Projektdauer	Aug 2002 to Jul 2004