Niggli
Fakultäten » Medizinische Fakultät » Kinderspital Zürich: Medizinische Klinik » Onkologie, Abteilung » Prof. Dr. Felix Niggli » Niggli
Completed research project
| Title / Titel | Establishing of minimal residual disease techniques in childhood acute lymphoblastic leukemia and their application in an international clinical treatment trial | ||||
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| Abstract (PDF, 14 KB) | |||||
| Summary / Zusammenfassung | Recent investigations have found that the dynamics of the decrease of tumor burden after initiation of treatment seems to influence the outcome of the disease substantially. Monitoring of minimal residual disease (MRD) in patients with hematopoietic malignant disorders is therefore a very important diagnostic tool to assess treatment response and the individual risk of relapse. We would like to use our expertise in quantitative detection of MRD in patients with childhood acute lymphoblastic leukemia (ALL) to make a significant contribution to the international leading clinical trials in this field | ||||
| Keywords / Suchbegriffe | minimal residual disease, childhood leukaemia, risk factors, real-time PCR | ||||
| Project leadership and contacts / Projektleitung und Kontakte |
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| Funding source(s) / Unterstützt durch |
Foundation Forschungsstiftung Kind und Krebs |
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| Duration of Project / Projektdauer | Jan 2000 to Dec 2004 |