Maissen
Fakultäten » Medizinische Fakultät » Neuropathologie, Institut für » Prof. Dr. Adriano Aguzzi » Maissen
Completed research project
| Title / Titel | Rescue of Scrapie-infected Mouse Neuroblastoma (N2aSc) Cells | ||||
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| Abstract (PDF, 14 KB) | |||||
| Summary / Zusammenfassung | There have been several publications in the last few years, showing that culturing cells chronically infected with prions with certain substrates would inhibit the PrPSc accumulation. According to our observations, it seems that the PrPSc formation of N2aSc cells can be reduced by putting the cells under stress in general. We are currently investigating whether the general stress reaction of the N2aSc cells is responsible for the reduction of the PrPSc levels. | ||||
| Keywords / Suchbegriffe | scrapie-infected mouse neuroblastoma (N2aSc) cells, stress reaction, PrPSc reduction | ||||
| Project leadership and contacts / Projektleitung und Kontakte |
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| Other links to external web pages | http://www.uzh.ch/pathol/neuropathologie/d/index.html | ||||
| Funding source(s) / Unterstützt durch |
Other Public Sources (e.g. Federal or Cantonal Agencies) Bundesamt für Gesundheit |
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| Duration of Project / Projektdauer | Jan 2001 to Dec 2003 |