Schoenle
Fakultäten » Medizinische Fakultät » Kinderspital Zürich: Medizinische Klinik » Endokrinologie/Diabetologie, Abteilung » Prof. Dr. Eugen Schönle » Schoenle
Current research project
| Title / Titel | Epidemiology of Type 1 Diabetes mellitus in Switzerland | ||
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| Abstract (PDF, 14 KB) | |||
| Summary / Zusammenfassung | In this nationwide prospective study we want to verify the trend of increasing diabetes incidence data from our earlier retrospective analysis of the military registry of Swiss males. The data collection of newly diagnosed children in Switzerland below age 15.0 years started in 1991 and is ongoing. The countrywide survey using a small questionnaire is sent to diabetes centers and diabetologists in the whole country. The questionnaire is anonymous. General data of the population are continuously taken from publications of the Swiss Federal Statistical Office. In the first evaluation of the data, the incidence in children aged 0-14 years rose significantly between 1991 and 1999 with a yearly average increase of 5.1 %. In the age group 0-4 years a more than 4-fold increase in incidence from 2.4/100’000 per year to 10.5/100’000 per year (p=0.0002) was recorded, whereas the age-specific incidence in the 5-9 years old and 10-14 years old children remained unchanged during the collection period. The incidence was significantly higher in boys than in girls, whereas no difference was found between rural and urban populations. This shows, that the incidence in type 1 diabetes is rising in children living in Switzerland but only the youngest age group of under 5 years is affected showing a dramatic annual average increase of 23.8 %. The study is prospectively ongoing. Raw data seem to show an even sharper rise in incidence of type 1 diabetes in children in the past few years. |
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| Publications / Publikationen | Schoenle, E.J., Lang-Muritano M., Gschwend, S., Laimbacher J., Mullis P.E., Torresani, T., Bi-ason-Lauber, A., Molinari L.: Epidemiology of Type 1 Diabetes mellitus in Switzerland: Steep Rise in Incidence in Under 5 Year Old Children in the Past Decade. Diabetologia 2001; 44:286-289Schoenle, E.J., Molinari, L., Bagot, M., Semadeni, S., Wiesendanger, M.: Epidemiology of insulin-dependent diabetes mellitus in Switzerland: Increasing incidence rate and rural-urban difference in Swiss men born between 1948-1972. Diabetes Care, 1994, 17:955-60EURODIAB ACE study group (member and coauthor E. J. Schoenle): Variation and trends in childhood diabetes in Europe. Lancet 2000;355:873-876 | ||
| Project leadership and contacts / Projektleitung und Kontakte |
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| Funding source(s) / Unterstützt durch |
No project-specific funding |
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| Duration of Project / Projektdauer | Jan 1991 to Jun 2015 |