Lutz
Fakultäten » Vetsuisse-Fakultät » Nutztiere, Departement für » Veterinärmedizinisches Labor » Prof. Dr. Regina Hofmann-Lehmann » Lutz
Completed research project
| Title / Titel | Concurrent infections with vector-borne pathogens as etiology of fatal hemolytic anemia in a cattle herd from Switzerland | ||||||
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| Abstract (PDF, 14 KB) | |||||||
| Summary / Zusammenfassung | Bovine anaplasmosis is a vector-borne disease resulting in substantial economic losses in other parts of the world but so far not in northern Europe. In August 2002, a fatal disease outbreak was reported in a large dairy herd in the Swiss Canton of Grisons. Diseased animals experienced fever, anorexia, agalactia, and depression. Anemia, ectoparasite infestation, and occasionally hemoglobinuria were observed. It was the goal of the present study to determine the role of vector-borne pathogens in the reported disease outbreak and to objectify the disease by laboratory methods. Infections with Anaplasma marginale, Anaplasma phagocytophilum, Babesia and Theileria spp., and Mycoplasma wenyonii were investigated by microscopical examination of blood smears, serologically and by molecular methods. It was found that A. marginale was the major cause of hemolytic anemia, while coinfections with other agents exacerbated the disease. We reported the first severe disease outbreak associated with concurrent infections of vector-borne pathogens in alpine Switzerland. |
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| Publications / Publikationen | Hilpertshauser, H., P. Deplazes, M. L. Meli, R. Hofmann-Lehmann, H. Lutz, and A. Mathis. 2007. Genotyping of Babesia bigemina from an unexpected outbreak in a cattle herd in Switzerland. Vet Parasitol. 2007 Jan 5; [Epub ahead of print].Dreher, U.M., J. de la Fuente, R. Hofmann-Lehmann, M. L. Meli, N. Pusterla, K. M. Kocan, Z. Woldehiwet, U. Braun, and H. Lutz. 2005. Serologic cross reactivity between Anaplasma marginale and Anaplasma phagocytophilum. Clin Diagn Lab Immunol 12: 1177-1183.Dreher, U.M., R. Hofmann-Lehmann, M.L. Meli, G. Regula, A.Y. Cagienard, K.D.C. Stärk, M.G. Doherr, F. Filli, M. Hässig, U. Braun, K.M. Kocan, and H. Lutz. 2005. Seroprevalence of anaplasmosis among cattle in Switzerland in 1998 and 2003: No evidence of an emerging disease. Vet Microbiol 107: 71-79.Hofmann-Lehmann, R., M. L. Meli, U. M. Dreher, E. Gönczi, P. Deplazes, U. Braun, M. Engels, J. Schüpbach, K. Jörger, R. Thoma, C. Griot, K. D. C. Stärk, B. Willi, J. Schmidt, K. M. Kocan, and H. Lutz. 2004. Concurrent infections with vector-borne pathogens associated with fatal hemolytic anemia in a cattle herd in Switzerland. J Clin Microbiol; 3775-3780.Brülisauer, F., R. Thoma, A. Cagienard, R. Hofmann-Lehmann, H. Lutz, M. L. Meli, G. Regula, K. Jörger, R. Perl, U. M. Dreher, U. Braun, K. D. C. Stärk. 2004. Anaplasmose in einem Milchviehbetrieb in Graubünden: Epidemiologische Ausbruchuntersuchung. Schweiz Arch Tierheilkd 146: 451-459. | ||||||
| Keywords / Suchbegriffe | Vector-borne pathogens, cattle, Anaplasma marginale, epidemiology, Theileria, Babesia, hemotropic Mycoplasma | ||||||
| Project leadership and contacts / Projektleitung und Kontakte |
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| Funding source(s) / Unterstützt durch |
Other Public Sources (e.g. Federal or Cantonal Agencies) |
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| In collaboration with / In Zusammenarbeit mit |
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| Duration of Project / Projektdauer | Aug 2002 to Aug 2004 |