Valsangiacomo-Buechel
Fakultäten » Medizinische Fakultät » Kinderspital Zürich: Medizinische Klinik » Kardiologie, Abteilung » Prof. Dr. Urs Bauersfeld (verstorben) » Valsangiacomo-Buechel
Completed research project
| Title / Titel | The fate of children with microdeletion 22q11 syndrome and congenital heart defect: clinical course and cardiac outcome | ||
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| Abstract (PDF, 14 KB) | |||
| Summary / Zusammenfassung | Congenital heart defects , particularly conotruncal malformations are a major feature of the microdeletion 22q11 syndrome. The prevalence of these cardiac lesions and the overall clinical features are well known but information about the clinical course is scarce. This project analyzes retrospectively the cardiac outcome of children with deletion 22q11 and congenital heart disease during long-term follow-up. The clinical history of all consecutive children who were treated in our institution between 1978 and 2003 is reviewed with particular attention to mortality, cardiac and extracardiac morbidity, primary cardiac surgical repair and cardiac reinterventions during follow up, including cardiac surgery and catheter-guided interventions. With these data we will be able to describe the potential influence of the genetic and the cardiac anomalies on the clinical course. |
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| Keywords / Suchbegriffe | Deletion 22q11, congenital heart disease, clinical outcome | ||
| Project leadership and contacts / Projektleitung und Kontakte |
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| Funding source(s) / Unterstützt durch |
Others Part of a thesis |
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| Duration of Project / Projektdauer | Jan 2003 to Dec 2005 |