Fakultäten » Medizinische Fakultät » Psychiatrische Universitätsklinik » Affektive Erkrankungen und Allgemeinpsychiatrie Zürich Ost, Klinik für » Prof. Dr. Erich Seifritz » Böker
| Title / Titel | Evaluation Of The Course Of The In-Patient Treatment Of Depressed Patients | ||||
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| Abstract (PDF, 14 KB) | |||||
| Summary / Zusammenfassung | Patients with Major Depression suffer from severe emotional and cognitive disturbances. Emotional symptoms consist in predominance of negative emotional experience as reflected in extreme anxiety and sadness. Cognitive symptoms include overgeneralization, selective abstraction, arbitrary inference etc.. The neuropsychological and psychopathological profile is investigated in the course of the in-patient treatment. The neuropsychological tests and psychopathological scales are applied right after the admittance, after three weeks and before discharge from the unit. Results show continuing neuropsychological deficits in patients with MDD during the remitted phase of the illness. Persistent deficits in sustained attention, the mnemonic and strategic aspects of working memory and executive function associated with altered prefrontal neural activity patterns might be considered a trait marker. Since the performance in visual learning and memory improved significantly, it can be assumed that impairments in these domains represent a depression-related state effect rather than a trait marker for MDD. |
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| Publications / Publikationen | Schulze, J. (2011, in prep.) Depressiv Erkrankte im Verlauf der stationären Depressionsbehandlung - Empirische Untersuchungen zu Psychopathologie und Neuropsychologie -. Med. Diss., Universität ZürichSchulze, J., Michels, C., Schnorf, M., Hell, D., Boeker, H. (2006) Neuropsychologische Funktionen und psychopatologische Befunde bei Depressionen im Verlauf der stationären Behandlung. DGPPN-Kongress 2006. Nervenarzt 77, Suppl. 3, 340-341Schulze, J., Grimm , S., Boeker, H. (2006) Depression and anxiety: Psychopathology, neuropsychology and personality traits in depressed patients in the course of in-patient treatment. German J Psychiatry 9: 6-7Böker H. (2003) Die interpersonale und kommunikative Dimension der Depression. In: Stationäre Depressionsbehandlumg heute. Wolfersdorf M., Kornacher J., Rupprecht U. (eds.), pp. 17-53, S. Roderer Verlag, RegensburgBöker H. (2003) Die partnerschaftlich verstrickte Depression. In: Die Crux mit der Praxis – Depressionsbehandlung im Alltag. Katschnig H., Demal U. (eds.), pp 45-63 , Facultas, WienBöker H., Hell D. (2002) (eds.) Therapie der affektiven Störungen: Psychosoziale und neurobiologische Perspektiven. 382 pp., Schattauer, Stuttgart, New York | ||||
| Keywords / Suchbegriffe | Depression, Neuropsychology, Evaluation Of the Inpatient Treatment | ||||
| Project leadership and contacts / Projektleitung und Kontakte |
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| Funding source(s) / Unterstützt durch |
Universität Zürich (position pursuing an academic career), Others |
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| Duration of Project / Projektdauer | Jan 2005 to Dec 2012 |