Lutz
Fakultäten » Philosophische Fakultät » Psychologisches Institut » Neuropsychologie » Prof. Dr. Lutz Jäncke » Lutz
Completed research project
| Title / Titel | Investigating Dentine Hypersensitivity using fMRI | ||||
|---|---|---|---|---|---|
| Abstract (PDF, 14 KB) | |||||
| Summary / Zusammenfassung | Dentine Hypersensitivity has recently been defined as a “short, sharp pain arising from exposed dentin in response to stimuli typically thermal, evaporative, tactile, osmotic or chemical and which cannot be ascribed to any other form of dental defect or disease. Studies conducted to measure changes in discomfort from one tooth to another, or changes over time due to a treatment have been moderately successful. A key limitation is that all methods rely on the patient to report stimulus related pain or subjective reports of having experienced relief. The Project aims at localizing and objectively describing the central processing of these painful sensations. A further goal is to relate the physical properties of the stimulus and the psychophysical properties of the sensation to the amplitude, spatial extents and time course of fMRI signal changes. Milestones for the Project, which is designed to last for three years, are the development of a multivalve, MRI compatible, automatically controlled stimulation system to apply gas jets with controllable temperature and pressure, the topographic brain mapping of stimulus perception at different teeth, intensity mapping in healthy volunteers and patients with dentine hypersensitivity. |
||||
| Project leadership and contacts / Projektleitung und Kontakte |
|
||||
| Funding source(s) / Unterstützt durch |
Private Sector (e.g. Industry) Glaxo Smith Cline, London |
||||
| In collaboration with / In Zusammenarbeit mit |
|
||||
| Duration of Project / Projektdauer | Dec 2005 to Dec 2009 |