Müller
Fakultäten » Medizinische Fakultät » Rheumaklinik und Institut für physikalische Medizin » PD Dr. Anne Mannion » Müller
Completed research project
| Title / Titel | Defining norm values on the natural history of acute and chronic low back pain in the Swiss population and prognostic indicators for chronic low back pain | ||||||||
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| Abstract (PDF, 14 KB) | |||||||||
| Original title / Originaltitel | Bestimmung von Normwerten des natürlichen Verlaufes von Kreuzschmerzen in der schweizer Bevölkerung und Definition von prädiktiven Faktoren für die chronifizierung von akuten | ||||||||
| Summary / Zusammenfassung | Introduction: Low back pain is a common problem in Switzerland, as elsewhere, and is a major cause of healthcare costs in the working and aging population. Goals of the Study: 1. to define norm values for ‘limitations in activities of daily living’ (L-ADL) in relation to the natural history of acute and chronic low back pain. 2. to define norm values on direct and indirect costs of low back pain. 3. to identify predictors of chronicity in acute low back pain patients. To reach these goals an interdisciplinary approach will be used. Present Knowledge: There is a vast amount of literature on predictive factors and on the natural history of low back pain, but few studies fulfill the criteria of a valid study design as revealed in a recent metanalysis by Pengel et al. [42]. Own investigations: In a population based, cross-sectional study we defined norm values for activities of daily living, psychological factors, working conditions, involvement in sports activities, general health perception, and other variables, in a random sample of 16`490 out of 23`763 (69.4%) German speaking individuals who were asked to complete the “Standard Evaluation Questionnaire” (SEQ). The results of a similar survey will be available in March 2004 for the Swiss French-speaking population. These cross-sectional data represent the basis for the present proposal. Method: Prospective cohort study design nested in a population-based cross-sectional study. Based on the existing dataset (see own investigations) low back pain (LBP) patients will be identified and classified into three groups: 1. acute LBP, 2. chronic LBP 3. control group (no LBP). A telephone interview will be conducted with individuals in each group and all individuals will be encouraged to complete a follow-up questionnaire (SEQ). A subsample of at least 100 individuals in each group will deliver more in-depth data by means of a pain and cost diary. Expected Results: Age and gender related L-ADL norm values for the natural history of acute and chronic low back pain will be established. Norm values on direct and indirect costs in connection with the natural course of low back pain will also be evaluated, with the focus on diagnostic measures and their consequences with respect to therapeutic measures. Further, potential predictor factors for the development of chronic low back pain will be identified, which will be validated, prospectively, in our future studies. Expected benefits: Norm L-ADL data for the natural history of low back pain will set the future benchmark for all treatments for low back pain. The relative effectiveness of new treatment modalities and procedures will be assessed and compared with the natural history, as revealed by the norm L-ADL data. The L-ADL data will be supplemented with norm values on the direct and indirect costs of low back pain. At the micro level, this will help health care providers to decide on preventive, diagnostic and therapeutic measures in the perspective of total quality management. At the macro level, the assessment of the epidemiology of low back pain in relation to the estimated social economic impact will provide decision makers with useful information to help them decide how best to allocate their limited health care resources. In this respect, this study will serve as a basis for future scientific work in low back pain outcome assessment. All these findings are thus likely to be relevant for our future health care system. |
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| Publications / Publikationen | 1. Tamcan O, Mannion AF, Eisenring C, Horisberger B and Müller U. (2005) Defining prognostic indicators and norm values for the natural history of acute and chronic low back. 2nd HTA (Health Technology Assessment) Annual Meeting, Rome, Italy, 20-22.6.05. Italian Journal of Public Health: 2. Mannion AF, Tamcan O, Eisenring B, Horisberger B, Elfering A and Mueller U. (2006) The influence of patients’ beliefs on their care-seeking behaviour for low back pain. 5th Congress of The European Federation of IASP, Istanbul, Turkey, 13-16.9.2006. Eur J Pain 10 (Supp 1): S107-108. 3. Mannion AF, Tamcan O, Eisenring C, Horisberger B and Mueller U. (2006) The association between beliefs about low back pain, work absence and productivity at work. Spine Society of Europe, Istanbul, Turkey, 25-28.10.2006. Eur Spine J 15 (Suppl 4): S474. 4. Tamcan O, Mannion AF, Eisenring C, Horisberger B and Mueller U. (2006) The association between beliefs about low back pain and work absence in a working population. The European Association for Behavioural and Cognitive Therapies, Paris, France, 20-23.9.2006. 5. Tamcan Ö, Mannion AF, Müller U (2008) Do we really need a pain diary for the reliable assessment of pain and related limitation? Results from a longitudinal prospective cohort study. UK Society for Back Pain Research, Keele University, UK. 6-7.11.2008 6. Mannion AF, Horisberger B, Eisenring C, Tamcan O, Elfering A, Mueller U (2009) The association between beliefs about low back pain and work presenteeism. J Occup Environ Med. 51(11):1256-1266 7. Elfering A, Mannion AF, Jacobshagen N, Tamcan O, Müller U.Beliefs about back pain predict the recovery rate over 52 consecutive weeks. Scand J Work Environ Health. 2009 Nov;35(6):437-45. 8. Tamcan O, Mannion AF, Eisenring C, Horisberger B, Elfering A, Dietrich D, Mueller U. The Course of Chronic and Recurrent Low Back Pain in the General Population. Pain 2010 Sep;150(3):451-7 9. Wieser S, Horisberger B, Schmidhauser S, Eisenring C, Bruegger U, Ruckstuhl A, Dietrich J, Mannion AF, Elfering A, Tamcan O, Mueller U. (2010) Cost of low back pain in Switzerland in 2005. Eur J Health Econ. 2011 Oct;12(5):455-67. 10. Wieser S, Mannion AF, Eisenring C, Elfering A, Bruegger U, Mueller U and Horisberger B. Production losses due to low back pain while at work and out of it. International Society for the Study of the Lumbar Spine, Gothenburg, Sweden, 14-18.06.2011 |
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| Keywords / Suchbegriffe | low back pain, survey, epidemiology | ||||||||
| Project leadership and contacts / Projektleitung und Kontakte |
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| Funding source(s) / Unterstützt durch |
SNF (Programm NFP), Foundation NFP53 "Musculoskeletal Health - Chronic Pain" (Project 405340-104826/1) and AO Spine |
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| Duration of Project / Projektdauer | Oct 2004 to Mar 2011 |