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Lauener

Fakultäten » Medizinische Fakultät » Kinderspital Zürich: Medizinische Klinik » Medizinische Klinik » PD Dr. Roger-Pascal Lauener (ausgetreten) » Lauener

Completed research project

Title / Titel Innate immune response
PDF Abstract (PDF, 14 KB)
Publications / Publikationen -) Lauener RP et al. 2002. Expression of CD14 and Toll-like receptor 2 differs between farmers’ and non-farmers’ children. The Lancet 360:465-466
-) Braun-Fahrländer C et al. 2002. Environmental exposure to microbial products (endotoxin) is inversely related to atopic asthma, hay fever and atopic sensitisation in school-aged children. New England Journal of Medicine 19;347(12):869-77
-)Seibl, R et al. 2003. Expression and regulation of Toll-like receptor 2 in rheumatoid arthritis synovium. American Journal of Pathology 162(4):1221-1227
-) Melén E et al. 2005. G-protein-coupled receptor for asthma susceptibility (GPRA) haplotypes are associated with childhood allergy and asthma - the PARSIFAL and BAMSE studies. Am J Respir Crit Care Med. 171:1089-95
-) Ege MJ et al. Prenatal farm exposure is related to the expres-sion of receptors of the innate immunity and to atopic sensitization in school-age children. J Allergy Clin Immunol 2006;117:817-23
-) Gerhold K et al. 2006. Prenatal initiation of endotoxin airway exposure prevents subsequent allergen-induced sensitization and airway inflammation in mice. J Allergy Clin Immunol. 2006; 118:666-73
-) Waser M et al. Inverse association of farm milk consumption with asthma and allergy in rural and suburban across Europe: Consumption of farm milk protects against asthma and allergy. Clin Exp Allergy (in press).
-) Schaub B et al. The many faces of the hygiene hypothesis. Journal of Allergy and Clinical Immunology 2006 (5): 969 (Review)
Project leadership and contacts /
Projektleitung und Kontakte
PD Dr. Roger Lauener, MD (Project Leader) Roger.Lauener@kispi.uzh.ch
Funding source(s) /
Unterstützt durch
Universität Zürich (position pursuing an academic career), SNF (Personen- und Projektförderung), EU, Foundation
Foundation: Kühne-Stiftung, Schindellegi
In collaboration with /
In Zusammenarbeit mit
Prof. Dr. Charlotte Braun-Fahrländer
Institut für Sozial- und Präventivmedizin
Universitäts Basel

Prof. Dr. C. Akdis
SIAF, Universität Zürich
Switzerland

Prof. Dr. Erika von Mutius
Universität München

Prof. Dr. H. Renz
Universität Marburg

Germany

Prof. Dr. Donata Vercelli
University of Arizona, Tucson

United States

Duration of Project / Projektdauer Jan 2002 to Dec 2008