Fakultäten » Medizinische Fakultät » Kinderspital Zürich: Medizinische Klinik » Entwicklungspädiatrie, Abteilung » Prof. Dr. Reto Huber » Huber
| Title / Titel | Sleep and brain plasticity during development | ||||||
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| Abstract (PDF, 14 KB) | |||||||
| Summary / Zusammenfassung | Children spend half of their lives asleep (Iglowstein et al., 2003). This increased sleep need is accompanied by extensive learning processes during the day. Because of the intertwined relationship between sleep and wakefulness (Borbély, 1982; Jenni and LeBourgeois, 2006) the question arises whether sleep and learning share common mechanisms in developmental processes of the brain. This question is of particular clinical interest because a large percentage of children suffer from sleep disorders (~ 20-30%; (Mindell et al., 1999) and/or learning disabilities (e.g. up to 10% of the children require special schooling in Switzerland; (Walther-Müller and Häfeli, 2005). Is there a direct link between sleep disorders and learning disabilities? To address this question the relationship between sleep and learning in children and adolescents needs to be examined. We propose to address this question by using a combination of high-density electroencephalographic (hd-EEG) recordings, and visuomotor learning tasks in children and adolescents. | ||||||
| Publications / Publikationen | Kurth, S; Ringli, M; Geiger, A; LeBourgeois, M; Jenni, O G; Huber, R (2010). Mapping of cortical activity in the first two decades of life: a high-density sleep electroencephalogram study. Journal of Neuroscience, 30(40):13211-13219.Buchmann, A; Ringli, M; Kurth, S; Schaerer, M; Geiger, A; Jenni, O G; Huber, R (2011). EEG Sleep Slow-Wave Activity as a Mirror of Cortical Maturation. Cerebral Cortex, 21(3):607-615.Kurth, S; Jenni, O G; Riedner, B A; Tononi, G; Carskadon, M A; Huber, R (2010). Characteristics of sleep slow waves in children and adolescents. Sleep, 33(4):475-480.Ringli, M; Huber, R (2011). Developmental aspects of sleep slow waves: linking sleep, brain maturation and behavior. Progress in Brain Research, 193:63-82.Weitere Informationen | ||||||
| Keywords / Suchbegriffe | Sleep EEG, cortical plasticity, visuomotor learning, children, adolescent | ||||||
| Project leadership and contacts / Projektleitung und Kontakte |
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| Other links to external web pages | http://www.kispi.uzh.ch/sleep | ||||||
| Funding source(s) / Unterstützt durch |
SNF (Personen- und Projektförderung) |
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| Duration of Project / Projektdauer | Jul 2007 to Jun 2011 |