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Huber

Fakultäten » Medizinische Fakultät » Kinderspital Zürich: Medizinische Klinik » Entwicklungspädiatrie, Abteilung » Prof. Dr. Reto Huber » Huber

Completed research project

Title / Titel Sleep and brain plasticity during development
PDF Abstract (PDF, 14 KB)
Summary / Zusammenfassung Children spend half of their lives asleep (Iglowstein et al., 2003). This increased sleep need is accompanied by extensive learning processes during the day. Because of the intertwined relationship between sleep and wakefulness (Borbély, 1982; Jenni and LeBourgeois, 2006) the question arises whether sleep and learning share common mechanisms in developmental processes of the brain. This question is of particular clinical interest because a large percentage of children suffer from sleep disorders (~ 20-30%; (Mindell et al., 1999) and/or learning disabilities (e.g. up to 10% of the children require special schooling in Switzerland; (Walther-Müller and Häfeli, 2005). Is there a direct link between sleep disorders and learning disabilities? To address this question the relationship between sleep and learning in children and adolescents needs to be examined. We propose to address this question by using a combination of high-density electroencephalographic (hd-EEG) recordings, and visuomotor learning tasks in children and adolescents.
Publications / Publikationen Kurth, S; Ringli, M; Geiger, A; LeBourgeois, M; Jenni, O G; Huber, R (2010). Mapping of cortical activity in the first two decades of life: a high-density sleep electroencephalogram study. Journal of Neuroscience, 30(40):13211-13219.

Buchmann, A; Ringli, M; Kurth, S; Schaerer, M; Geiger, A; Jenni, O G; Huber, R (2011). EEG Sleep Slow-Wave Activity as a Mirror of Cortical Maturation. Cerebral Cortex, 21(3):607-615.

Kurth, S; Jenni, O G; Riedner, B A; Tononi, G; Carskadon, M A; Huber, R (2010). Characteristics of sleep slow waves in children and adolescents. Sleep, 33(4):475-480.

Ringli, M; Huber, R (2011). Developmental aspects of sleep slow waves: linking sleep, brain maturation and behavior. Progress in Brain Research, 193:63-82.

Weitere Informationen

Keywords / Suchbegriffe Sleep EEG, cortical plasticity, visuomotor learning, children, adolescent
Project leadership and contacts /
Projektleitung und Kontakte
Prof. Dr. Reto Huber, PhD (Project Leader) reto.huber@kispi.uzh.ch
Other links to external web pages http://www.kispi.uzh.ch/sleep
Funding source(s) /
Unterstützt durch
SNF (Personen- und Projektförderung)
 
In collaboration with /
In Zusammenarbeit mit
PD Dr. Oskar Jenni, Director of the Child Development Center, University Children’s Hospital Zurich Switzerland

Prof. Dr. Bernhard Schmitt, Director of the EEG Department, University Children’s Hospital Zurich

Switzerland

Prof. Dr. Irene Tobler, Group leader, Institute of Pharmacology and Toxicology, University of Zurich

Switzerland

Duration of Project / Projektdauer Jul 2007 to Jun 2011