Moeller
Fakultäten » Medizinische Fakultät » Kinderspital Zürich: Medizinische Klinik » Pneumologie » PD Dr. Alexander Möller » Moeller
Current research project
| Title / Titel | Standardized exercise challenge test for preschool children using the Forced oscillation technique | ||||
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| Abstract (PDF, 14 KB) | |||||
| Summary / Zusammenfassung | Background: Asthma diagnosis and documentation of disease control in preschool children is difficult. Exercise induced bronchoconstriction (EIB) is a common feature of childhood asthma and tests to evaluated EIB are established for school-children. As young preschool-children are not able to cooperate to perform Spirometry, the gold standard of EIB-testing, no standardized test is available for children younger than 6 years. Aims: To evaluate a standardized EIB-test for children between 3 and 6 years. Methods: 150 children aged 3 to 6 years are included in a cross-sectional study. 100 with a doctor diagnosed asthma and 50 healthy controls. Children are running together with the investigator in order to achieve submaximal heart rate (>195b/min, Polar®) within 2 minutes and to keep this heart rate for 4 minutes. Lung function is assessed by forced oscillation technique (FOT) and is performed at baseline and at 3, 6, 10, 15 minutes after the run. A positive EIA isdefined as an increase in resistance of ≥30 % in Rrs4-24Hz or 32% in Rrs8Hz to baseline. |
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| Publications / Publikationen | no | ||||
| Keywords / Suchbegriffe | EIA test, Asthma, preschool children, Forced oscillation technique | ||||
| Project leadership and contacts / Projektleitung und Kontakte |
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| Funding source(s) / Unterstützt durch |
Foundation Hartmann Mueller Stiftung |
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| In collaboration with / In Zusammenarbeit mit |
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| Duration of Project / Projektdauer | Jan 2007 to Apr 2012 |